Journal article
Water toxicity detection by a panel of stress-responsive luminescent bacteria
Journal of applied toxicology, v 24(5), pp 343-348
Sep 2004
PMID: 15478173
Abstract
A panel of Escherichia coli strains harbouring different stress-responsive promoters fused to a lux reporter system was used to assess the potential toxicity of 17 unknown model water samples. Using liquid cultures, nine out of 14 toxic samples were properly identified as toxic, whereas five were false negatives. All three non-toxic controls were identified correctly (no false positives). Two strains containing promoter-lux fusions were also tested when immobilized onto fibre-optic tips. One genotoxic sample and six toxic samples were correctly identified in this manner. The potential advantages and limitations in the use of genetically engineered bacteria as biosensors for water toxicity are discussed in view of these results.
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Details
- Title
- Water toxicity detection by a panel of stress-responsive luminescent bacteria
- Creators
- R Pedahzur - Division of Environmental Sciences, The Fredy and Nadine Herrmann Graduate School of Applied Science, The Hebrew University of Jerusalem, Jerusalem 91904, Israel. ramip@pob.huji.ac.ilB PolyakR S MarksS Belkin
- Publication Details
- Journal of applied toxicology, v 24(5), pp 343-348
- Publisher
- Wiley; England
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:000224592100007
- Scopus ID
- 2-s2.0-6944226175
- Other Identifier
- 991014878361704721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Toxicology