Journal article
Wear, Material Transfer, and Electrocautery Damage Are Ubiquitous on CoCrMo Femoral Knee Retrievals
Journal of biomedical materials research. Part B, Applied biomaterials, v 112(12), e35504
Dec 2024
PMID: 39563654
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Despite high total knee arthroplasty (TKA) survivorship after 10 years (92%–99%), a gap persists where patient satisfaction lags clinical success. Additionally, while cobalt chrome molybdenum (CoCrMo) use decreases in primary total hip arthroplasty, the alloy continues to be widely used in TKA femoral components. In vivo, CoCrMo degradation may be associated with adverse local tissue reactions (ALTR) and compared with the hip, the damage mechanisms that may release metal in the knee and the potential biological effects remain poorly understood. In this study, we characterized the damage on 50 retrieved CoCrMo femoral knee implants paired with 19 titanium alloy and 31 CoCrMo tibial baseplates. We asked (1) what damage modes can release CoCrMo debris in vivo from femoral components and (2) how frequently does the damage occur? First, we developed a semiquantitative scoring system for abrasive wear. Then, we characterized damage modes on CoCrMo femoral implants using digital optical microscopy (DOM), scanning electron microscopy (SEM), and energy dispersive X‐ray spectroscopy (EDS). We found that wear, electrocautery damage, and Ti‐6Al‐4V material transfer were ubiquitous. Of the 50 CoCrMo femoral implants we investigated, we documented wear on 100% ( n = 50/50), electrocautery damage on 98% ( n = 49/50), and Ti‐6Al‐4V material transfer to the posterior condyles on 95% ( n = 18/19). Our results suggest that these damage modes may be more prevalent than previously thought and may act as metal release mechanisms in vivo.
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Details
- Title
- Wear, Material Transfer, and Electrocautery Damage Are Ubiquitous on CoCrMo Femoral Knee Retrievals
- Creators
- Peter W. Kurtz - Clemson UniversityMichael A. Kurtz - Clemson UniversityShabnam Aslani - Drexel UniversityLilliana M. Taylor - Medical University of South CarolinaCharley M. Goodwin - Clemson UniversityDaniel W. MacDonald - Drexel UniversityNicolas S. Piuzzi - Cleveland ClinicWilliam M. Mihalko - Campbell ClinicSteven M. Kurtz - Drexel UniversityJeremy L. Gilbert (Corresponding Author) - Clemson University
- Publication Details
- Journal of biomedical materials research. Part B, Applied biomaterials, v 112(12), e35504
- Publisher
- Wiley
- Number of pages
- 15
- Grant note
- Ceramtec
Institutional support for this research was provided by Ceramtec.
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:001369916400001
- Scopus ID
- 2-s2.0-85210033914
- Other Identifier
- 991021963415704721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Engineering, Biomedical
- Materials Science, Biomaterials