Objectives To determine whether visual field (VF) damage or other factors confer a similar risk of falling when falls are ascertained as a rate over time (falls/year) as when ascertained over activity (falls/step). Design Prospective, observational cohort study. Setting Clinic-based recruitment with real-world monitoring of falls and physical activity. Particpants Individuals with glaucoma or suspected glaucoma (N=230). Measurements Participants recorded falls using daily calendars, with injuries identified in a follow-up questionnaire. Annual 1-week accelerometer trials were used to estimate steps. VF results from both eyes were merged to determine integrated VF sensitivity, with lower sensitivity indicating greater VF damage. Other potential risk factors for falls (age, sex, race, comorbid illness, polypharmacy) were determined using questionnaires. Results The cumulative probability of falls was 45.2% at 12 months and 61.6% at 24 months; cumulative probability of injurious falls was 23.3% at 12 months and 40.0% at 24 months. Greater VF damage was associated with higher rates of falls/steps (incident rate ratio = 1.40/5 dB decrement in sensitivity; p = .004) but not with more falls/year (incident rate ratio = 1.25/5 dB decrement in sensitivity; p = .07). Several additional variables (older age, female sex, more comorbid disease) were also associated with a higher rate of falls/step (p < .02 for all) but not with falls/year (p > 0.10). Black participants had fewer falls/year than whites (p = .002) but did not differ in falls/step (p = .07). Similar results were obtained when injurious falls were analyzed. Conclusions Risk factors associated with frequent falls when walking (falls/step) are not properly identified when analyzing falls as a rate over time (falls/year). Given the clinical importance of preventing falls while preserving physical activity, falls assessment integrated with activity measurement is recommended when determining whether a risk factor is associated with falls. J Am Geriatr Soc 67:87-92, 2019.
What Is a Falls Risk Factor? Factors Associated with Falls per Time or per Step in Individuals with Glaucoma
Creators
Pradeep Y. Ramulu - Johns Hopkins University
Aleksandra Mihailovic - Johns Hopkins University
Sheila K. West - Johns Hopkins University
David S. Friedman - Johns Hopkins University
Laura N. Gitlin - Drexel University
Publication Details
Journal of the American Geriatrics Society (JAGS), v 67(1)
Publisher
Wiley
Number of pages
6
Grant note
EY022976 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
R01EY022976 / NATIONAL EYE INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI)
Resource Type
Journal article
Language
English
Academic Unit
College of Nursing and Health Professions
Web of Science ID
WOS:000455035800014
Scopus ID
2-s2.0-85055699886
Other Identifier
991019168694804721
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