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Journal article
What Stroke Symptoms Tell Us: Association of Risk Factors and Individual Stroke Symptoms in the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study
Journal of stroke and cerebrovascular diseases, v 21(5), pp 411-416
Jul 2012
PMID: 22726606
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Stroke symptoms are common among people without a history of stroke or transient ischemic attack; however, it is unknown if particular attention should be focused on specific symptoms for subgroups of patients.
Using baseline data from 26,792 REasons for Geographic And Racial Differences in Stroke (REGARDS) participants without a history of transient ischemic attack or stroke, we assessed the association between age, sex, race, current smoking, hypertension, and diabetes and the 6 stroke symptoms in the Questionnaire for Verifying Stroke-Free Status.
The mean age of participants was 64.4 ± 9.4 years, 40.7% were black, and 55.2% were women. After multivariable adjustment, older persons more often reported an inability to understand (odds ratio [OR] 1.16 per 10 years older age; 95% confidence interval [CI] 1.07-1.25) and unilateral vision loss (OR 1.09; 95% CI 1.01-1.18) and less often reported numbness (OR 0.83; 95% CI 0.79-0.87) and weakness (OR 0.85; 95% CI 0.80-0.90). Women reported difficulty communicating more often than men (OR 1.36; 95% CI 1.19-1.56). The OR for blacks compared to whites for each of the 6 stroke symptoms was increased, markedly so for unilateral numbness (OR 1.97; 95% CI 1.81-2.16), unilateral weakness (OR 1.96; 95% CI 1.76-2.18), and inability to understand (OR 1.87; 95% CI 1.61-2.18). Current smoking, hypertension, and diabetes were associated with higher ORs for each stroke symptom.
The association of risk factors with 6 individual stroke symptoms studied was not uniform, suggesting the need to emphasize individual stroke symptoms in stroke awareness campaigns when targeting populations defined by risk.
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Details
- Title
- What Stroke Symptoms Tell Us: Association of Risk Factors and Individual Stroke Symptoms in the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study
- Creators
- Liyan Gao - University of Alabama at BirminghamJames F. Meschia - Jacksonville CollegeSuzanne E. Judd - University of Alabama at BirminghamPaul Muntner - University of Alabama at BirminghamLeslie A. McClure - University of Alabama at BirminghamVirginia J. Howard - University of Alabama at BirminghamJames D. Rhodes - University of Alabama at BirminghamMary Cushman - University of VermontMonika M. Safford - University of Alabama at BirminghamElsayed Z. Soliman - Wake Forest UniversityDawn O. Kleindorfer - University of CincinnatiGeorge Howard - University of Alabama at Birmingham
- Publication Details
- Journal of stroke and cerebrovascular diseases, v 21(5), pp 411-416
- Publisher
- Elsevier
- Grant note
- Department of Health and Human Services National Institutes of Health U01 NS041588 / National Institute of Neurological Disorders and Stroke
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000305616600013
- Scopus ID
- 2-s2.0-84862849193
- Other Identifier
- 991019231650504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Neurosciences
- Peripheral Vascular Disease