Files and links (1)
Published, Version of Record (VoR)CC BY-NC V4.0, Open
Journal article
Where there is sodium there may be sepsis
Journal of community hospital internal medicine perspectives, v 9(4), pp 296-299
05 Sep 2019
PMID: 31528275
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Hypernatremia affects up to 9% of critically ill patients upon hospital admission, especially in elderly patients with thirst impairment. However, hypernatremia is not entirely explained by fluid imbalance. Recent studies suggest that sodium is an important enhancer of the immune system, raising the question of whether inflammatory states such as sepsis may contribute to hypernatremia. Although sepsis patients with hypernatremia face a greater mortality rate, there is a lack of studies examining a potential association between hypernatremia and sepsis. Motivated by the frequent concurrence of hypernatremia and sepsis observed at an eastern Pennsylvanian community hospital, the current study was conducted to evaluate whether hypernatremia on admission may serve as a potential surrogate marker for sepsis. The medical records of 153 patients with hypernatremia on admission (serum sodium > 145mEq/L) were retrospectively analyzed. The mean age of patients was 81.1. Sepsis was observed in 77.1% of patients, of which 86.2% had dementia. This study demonstrated a positive correlation between hypernatremia on admission and the presence of sepsis. We suggest that the existence of hypernatremia should prompt clinicians to further investigate for sources of infection, especially in the elderly and patients with dementia.
Metrics
11 Record Views
Details
- Title
- Where there is sodium there may be sepsis
- Creators
- Gerson De Freitas - Easton HospitalAnuragh Gudur - Drexel UniversityMyriam Vela-Ortiz - Carroll County Nephrology, Carrollton, GA, USA.Jacek Jodelka - St. Luke's HospitalDavid Livert - Drexel UniversityMahesh Krishnamurthy - Easton Hospital
- Publication Details
- Journal of community hospital internal medicine perspectives, v 9(4), pp 296-299
- Publisher
- Taylor & Francis
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate); General Internal Medicine
- Web of Science ID
- WOS:000486035900003
- Other Identifier
- 991019169702604721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Critical Care Medicine