Journal article
Where to Focus Efforts to Reduce the Black-White Disparity in Stroke Mortality: Incidence Versus Case Fatality?
Stroke (1970), v 47(7), pp 1893-1898
Jul 2016
PMID: 27256672
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
At age 45 years, blacks have a stroke mortality ≈3× greater than their white counterparts, with a declining disparity at older ages. We assess whether this black-white disparity in stroke mortality is attributable to a black-white disparity in stroke incidence versus a disparity in case fatality.
We first assess if black-white differences in stroke mortality within 29 681 participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort reflect national black-white differences in stroke mortality and then assess the degree to which black-white differences in stroke incidence or 30-day case fatality after stroke contribute to the disparities in stroke mortality.
The pattern of stroke mortality within the study mirrors the national pattern, with the black-to-white hazard ratio of ≈4.0 at age 45 years decreasing to ≈1.0 at age 85 years. The pattern of black-to-white disparities in stroke incidence shows a similar pattern but no evidence of a corresponding disparity in stroke case fatality.
These findings show that the black-white differences in stroke mortality are largely driven by differences in stroke incidence, with case fatality playing at most a minor role. Therefore, to reduce the black-white disparity in stroke mortality, interventions need to focus on prevention of stroke in blacks.
Metrics
Details
- Title
- Where to Focus Efforts to Reduce the Black-White Disparity in Stroke Mortality: Incidence Versus Case Fatality?
- Creators
- George Howard - University of Alabama at BirminghamClaudia S Moy - National Institutes of HealthVirginia J Howard - University of Alabama at BirminghamLeslie A McClure - Drexel UniversityDawn O Kleindorfer - University of CincinnatiBrett M Kissela - University of CincinnatiSuzanne E Judd - University of Alabama at BirminghamFredrick W Unverzagt - University of VermontElsayed Z Soliman - Wake Forest UniversityMonika M Safford - Cornell UniversityMary Cushman - University of VermontMatthew L Flaherty - University of CincinnatiVirginia G Wadley - Cornell UniversityREGARDS Investigators
- Publication Details
- Stroke (1970), v 47(7), pp 1893-1898
- Grant note
- P30 DK079626 / NIDDK NIH HHS UL1 TR001425 / NCATS NIH HHS U01 NS041588 / NINDS NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000379844900046
- Scopus ID
- 2-s2.0-84973390144
- Other Identifier
- 991019168275904721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Peripheral Vascular Disease