[image omitted] Leukoaraiosis Severity and List-Learning in Dementia
Catherine C. Price, Kelly Davis Garrett, Angela L. Jefferson, Stephanie Cosentino, Jared J. Tanner, Dana L. Penney, Rodney Swenson, Tania Giovannetti, Brianne Magouirk Bettcher and David J. Libon
Clinical Neurology Life Sciences & Biomedicine Neurosciences & Neurology Psychology Psychology, Clinical Science & Technology Social Sciences
In patients with dementia, leukoaraiosis (LA) was hypothesized to result in differential patterns of impairment on a verbal serial list-learning test. Using a visual rating scale, 144 dementia patients with ischemic scores 4 were re-categorized as having mild (n = 73), moderate (n = 44), or severe LA (n = 27). Mild LA was predicted to be associated with an amnestic list-learning profile, while severe LA was predicted to be associated with a dysexecutive profile. List-learning performances were standardized to a group of healthy older adults (n = 24). Analyses were conducted on a set of four factors derived from the list-learning paradigm, as well as error scores. Data indicate that LA severity is an important marker for understanding list learning in dementia.
[image omitted] Leukoaraiosis Severity and List-Learning in Dementia
Creators
Catherine C. Price - University of Florida Health
Kelly Davis Garrett - LDS Hospital
Angela L. Jefferson - Boston University
Stephanie Cosentino - Columbia University Irving Medical Center
Jared J. Tanner - University of Florida Health
Dana L. Penney - Lahey Hospital and Medical Center
Rodney Swenson - University of North Dakota
Tania Giovannetti - Temple University
Brianne Magouirk Bettcher - Temple University
David J. Libon - Drexel University
Publication Details
Clinical neuropsychologist, v 23(6), pp 944-961
Publisher
Taylor & Francis
Number of pages
18
Grant note
K23NS060660 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS)
R03AG026610; K23AG030962; R03AG027480; R01AG021362; P30AG013846 / NATIONAL INSTITUTE ON AGING; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA)
Resource Type
Journal article
Language
English
Web of Science ID
WOS:000268178000003
Scopus ID
2-s2.0-68949164878
Other Identifier
991021901013104721
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Collaboration types
Domestic collaboration
Web of Science research areas
Clinical Neurology
Psychology
Psychology, Clinical
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