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Lack of the Cromer antigen GUTI in Mexican Americans and Choctaw Indians
Letter/Communication   Peer reviewed

Lack of the Cromer antigen GUTI in Mexican Americans and Choctaw Indians

Joann M Moulds, Thomas R Drames and Bolaji Thomas
Transfusion (Philadelphia, Pa.), v 44(2), pp 307-307
01 Feb 2004
PMID: 14962324

Abstract

Decay-accelerating factor (DAF) is a complement regulatory protein composed of four short-consensus repeats(SCRs), a serine-threonine-proline–rich region, and a glycosylphosphatidylinositol anchor.1 A series of single-amino-acid changes exist on DAF that are responsible for the Cromer blood group antigens including Tca/Tcb/Tcc,Esa, and WESa/WESb on SCR1; Dra on SCR3; and Cra and UMC on SCR4.2 The most recently discovered Cromer antigen, GUTI, is also located on SCR4 and was found in the Mapuche Indians of Chile.3 Accordingly, we extended the original studies by testing populations having Native American backgrounds. [1st paragraph]

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Hematology
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