Letter/Communication
More on Pulmonary Fibrosis Associated with Aluminum Trihydrate (Corian) Dust
The New England journal of medicine, v 371(10), pp 973-974
04 Sep 2014
PMID: 25184884
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To the Editor:
Raghu et al. (May 29 issue)1 reported a case of pulmonary fibrosis in the context of possible aluminum exposure due to sanding of Corian material. Findings in the lung tissue included both aluminum trihydrate and aluminum oxide. The authors cite the article by Jederlinic et al.2 in support of causation, but this at best shows only analogy, because aluminum trihydrate and aluminum oxide are distinct compounds. Aluminum oxide is a component of sandpaper; with the patient's history of sanding Corian, it is difficult to determine whether the pulmonary fibrosis is due to the aluminum trihydrate in Corian, the aluminum oxide in sandpaper, or another, unknown environmental exposure.
From a toxicologic perspective of chronic aluminum exposure, relevant details of the patient's disease course are unreported. There is no mention of pertinent positive or negative findings associated with chronic aluminum toxicity such as potroom asthma, osteomalacia, hypochromic microcytic anemia, or encephalopathy.3 The authors prove an exposure pathway but fail to identify the source.
Metrics
Details
- Title
- More on Pulmonary Fibrosis Associated with Aluminum Trihydrate (Corian) Dust
- Creators
- Rita McKeever - Drexel UniversityJolene Okaneku - Drexel UniversityGregory S LaSala - Drexel University
- Publication Details
- The New England journal of medicine, v 371(10), pp 973-974
- Publisher
- Massachusetts Medical Society
- Number of pages
- 2
- Resource Type
- Letter/Communication
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:000341390600030
- Scopus ID
- 2-s2.0-84906996714
- Other Identifier
- 991019353725704721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Medicine, General & Internal