Logo image
Polypill for Cardiovascular Disease Prevention in an Underserved Population
Letter/Communication   Open access   Peer reviewed

Polypill for Cardiovascular Disease Prevention in an Underserved Population

Usama Bilal and Miguel Cainzos-Achirica
The New England journal of medicine, v 382(1), pp 94-95
02 Jan 2020
PMID: 31875509
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://europepmc.org/articles/pmc7061282View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Cardiovascular Diseases Secondary Prevention Vulnerable Populations Humans Drug Combinations
Muñoz and colleagues found that the polypill can reduce cardiovascular risk among vulnerable persons at intermediate-to-high risk. Despite the promising findings,1 polypill approaches to primary prevention in low-income populations address the tip of a much larger iceberg, particularly if used regardless of baseline risk.1,2 Fundamental causes of disease,3 such as disadvantageous socioeconomic conditions, are at the root of a variety of adverse health outcomes, including cardiovascular disease and cancer, both of which disproportionately affect the poor. Fundamental causes operate through pathways that include unhealthy diets, sedentary behaviors, smoking, excessive alcohol consumption, and psychosocial stress.3 Interventions that ignore fundamental causes and focus on proximal factors let the former affect health through other mechanisms. Lack of structural interventions may explain the decline in life expectancy observed in the United States in recent years despite an 80% increase in statin use.4 We applaud efforts to improve therapeutic adherence and the management of cardiovascular risk among high-risk persons from underserved communities using polypills. However, before escalating these to larger populations with heterogeneous risks,1,2 we should work to invent a polypill against social injustice and poverty.

Metrics

14 Record Views

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Collaboration types
Domestic collaboration
Web of Science research areas
Medicine, General & Internal
Logo image