Magazine article
Exercise to Reduce Pain?
Paraplegia news, Vol.66(3), pp.33-34
01 Mar 2012
Abstract
Neuropathic pain is a chronic, devastating and complex condition that impairs the daily lives of more than two-thirds of individuals with spinal-cord injury (SCI). Despite the high incidence and debilitating nature of SCI-induced pain, cellular and molecular mechanism(s) responsible for its development and maintenance remain elusive, leading to the current gap in effective treatment. Research has shown that a decrease in the amount of glial cell-derived neurotrophic factor (GDNF) and arternin, two neurotrophic factors or proteins that promote survival of sensory neurons in the spinal cord, contributes to the development of chronic pain. Importantly, restoring the levels of GDNF and artemin to normal in the spinal cord can reduce aberrant changes in sensory nerves and, most importantly, weaken the feeling of pain. Here, Detloff narrates how an exercise can ease the discomfort of neuropathic pain.
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Details
- Title
- Exercise to Reduce Pain?
- Creators
- Megan Detloff - Drexel University
- Publication Details
- Paraplegia news, Vol.66(3), pp.33-34
- Publisher
- PVA Publications; Phoenix
- Number of pages
- 2
- Resource Type
- Magazine article
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Identifiers
- 991020111370404721