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Point-of-care oral-based diagnostics
Other   Open access   Peer reviewed

Point-of-care oral-based diagnostics

Rw Hart, Mg Mauk, C Liu, X Qiu, Ja Thompson, D Chen, D Malamud, Wr Abrams and Hh Bau
Oral diseases, v 17(8), pp 745-752
26 Apr 2011
PMID: 21521419
url
https://doi.org/10.1111/j.1601-0825.2011.01808.xView
Published, Version of Record (VoR) Open

Abstract

Article
Many of the target molecules that reside in blood are also present in oral fluids, albeit at lower concentrations. Oral fluids are, however, relatively easy and safe to collect without the need for specialized equipment and training. Thus, oral fluids provide convenient samples for medical diagnostics. Recent advances in lab-on-a-chip technologies have made minute, fully integrated diagnostic systems practical for an assortment of point-of-care tests. Such systems can perform either immunoassays or molecular diagnostics outside centralized laboratories within time periods ranging from minutes to an hour. The article briefly reviews recent advances in devices for point-of-care testing with a focus on work that has been carried out by the authors as part of a NIH program.

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41 citations in Scopus

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Collaboration types
Domestic collaboration
Web of Science research areas
Dentistry, Oral Surgery & Medicine
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