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Exploring Nutritional Impact on Alzheimer's Mortality: An Explainable AI Approach
Preprint   Open access

Exploring Nutritional Impact on Alzheimer's Mortality: An Explainable AI Approach

Ziming Liu, Longjian Liu, Robert E Heidel and Xiaopeng Zhao
ArXiv.org
25 May 2024
url
https://arxiv.org/abs/2405.17502View
Preprint (Author's original)arXiv.org - Non-exclusive license to distribute Open

Abstract

Computer Science - Artificial Intelligence Computer Science - Learning
This article uses machine learning (ML) and explainable artificial intelligence (XAI) techniques to investigate the relationship between nutritional status and mortality rates associated with Alzheimers disease (AD). The Third National Health and Nutrition Examination Survey (NHANES III) database is employed for analysis. The random forest model is selected as the base model for XAI analysis, and the Shapley Additive Explanations (SHAP) method is used to assess feature importance. The results highlight significant nutritional factors such as serum vitamin B12 and glycated hemoglobin. The study demonstrates the effectiveness of random forests in predicting AD mortality compared to other diseases. This research provides insights into the impact of nutrition on AD and contributes to a deeper understanding of disease progression.

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