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Neurons underlying aggressive actions that are shared by both males and females in Drosophila
bioRxiv
28 Feb 2024
PMID: 38464020
Abstract
Aggression involves both sexually monomorphic and dimorphic actions. How the brain implements these two types of actions is poorly understood. We found that a set of neurons, which we call CL062, previously shown to mediate male aggression also mediate female aggression. These neurons elicit aggression acutely and without the presence of a target. Although the same set of actions is elicited in males and females, the overall behavior is sexually dimorphic. The CL062 neurons do not express fruitless, a gene required for sexual dimorphism in flies, and expressed by most other neurons important for controlling fly aggression. Connectomic analysis suggests that these neurons have limited connections with fruitless expressing neurons that have been shown to be important for aggression, and signal to different descending neurons. Thus, CL062 is part of a monomorphic circuit for aggression that functions parallel to the known dimorphic circuits.Competing Interest StatementThe authors have declared no competing interest.
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Details
- Title
- Neurons underlying aggressive actions that are shared by both males and females in Drosophila
- Creators
- Liangyu Tao - Drexel UniversityDeven Ayambem - Swarthmore CollegeVictor Barranca - Swarthmore CollegeVikas Bhandawat - Drexel University
- Publication Details
- bioRxiv
- Publisher
- Cold Spring Harbor Laboratory Press; Cold Spring Harbor
- Resource Type
- Preprint
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Other Identifier
- 991021862725904721