Penetration Deep into Tissues of Reactive Oxygen Species Generated in Floating-Electrode Dielectric Barrier Discharge (FE-DBD): in Vitro Agarose Gel Model Mimicking an Open Wound
In this manuscript we present an in vitro model based on agarose gel that can
be used to simulate a dirty, oily, bloody, and morphologically complex surface
of, for example, an open wound. We show this models effectiveness in simulating
depth of penetration of reactive species generated in plasma deep into tissue
of a rat and confirm the penetration depths with agarose gel model. We envision
that in the future such a model could be used to study plasma discharges (and
other modalities) and minimize the use of live animals: plasma can be optimized
on the agarose gel wound model and then finally verified using an actual wound.
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Title
Penetration Deep into Tissues of Reactive Oxygen Species Generated in Floating-Electrode Dielectric Barrier Discharge (FE-DBD): in Vitro Agarose Gel Model Mimicking an Open Wound
Creators
Danil Dobrynin
Gregory Fridman
Gary Friedman
Alexander Fridman
Publication Details
ArXiv.org
Resource Type
Preprint
Language
English
Academic Unit
Electrical and Computer Engineering; C. and J. Nyheim Plasma Institute; Mechanical Engineering and Mechanics