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Recurrent autoimmune hemolytic anemia in splenic marginal zone lymphoma
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Recurrent autoimmune hemolytic anemia in splenic marginal zone lymphoma

Oreoluwa Oladiran, Rashmi Dhital and Anthony Donato
Journal of Community Hospital Internal Medicine Perspectives, v 8(4), pp 244-245
04 Jul 2018
PMID: 30181837
url
https://doi.org/10.1080/20009666.2018.1500422View
Published, Version of Record (VoR) Open

Abstract

autoimmune hemolytic anemia prednisone Rituximab splenectomy splenic marginal zone lymphoma
Autoimmune hemolytic anemia (AIHA) is a condition associated with an extensive differential diagnosis that includes lymphoid malignancies. Although AIHA occurs in about 10-25% of patients with chronic lymphocytic leukemia, it is also reported to occur in all of the other lymphoid subtypes. In this article, we report a case of recurrent AIHA in a 67-year-old woman with two acute episodes of hemolysis separated by 3 years of hematologic remission. Both episodes were severe enough to require blood transfusion, oral steroids, and rituximab. Bone marrow biopsy and immunophenotyping using flow cytometry done during both admissions confirmed the presence of splenic marginal zone lymphoma.

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Web of Science research areas
Hematology
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