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Environmental Factors in the Preconception and Prenatal Periods in Relation to Risk for ASD
Encyclopedia entry

Environmental Factors in the Preconception and Prenatal Periods in Relation to Risk for ASD

Kristen Lyall, Rebecca J. Schmidt and Irva Hertz-Picciotto
Handbook of Autism and Pervasive Developmental Disorders, Fourth Edition
14 Mar 2014

Abstract

nutrition gene‐by‐environment causes environmental chemicals autism spectrum disorder pollution lifestyle
Evidence is accumulating for potential contributions to ASD risk from preconception or prenatal maternal nutrition, lifestyle, infection, medications, and exposures to environmental chemicals. No single or universal cause is likely; rather, multiple genetic variants and noninherited factors appear to combine to affect each child's development. Key concepts for future research include specificity to ASD versus causes common to other neurodevelopmental conditions, gene‐by‐environment interactions, and critical windows of vulnerability that may vary by exposure.

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