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Asthma and Allergies in Children With Autism Spectrum Disorders: Results From the CHARGE Study
Journal article   Open access   Peer reviewed

Asthma and Allergies in Children With Autism Spectrum Disorders: Results From the CHARGE Study

Kristen Lyall, Judy Van de Water, Paul Ashwood and Irva Hertz-Picciotto
Autism research, v 8(5), pp 567-574
Oct 2015
PMID: 25722050
url
https://europepmc.org/articles/pmc6900397View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Asthma - epidemiology Autism Spectrum Disorder - epidemiology California - epidemiology Case-Control Studies Child, Preschool Comorbidity Female Humans Hypersensitivity - epidemiology Male Prevalence Risk
Immune aberrations are often noted in children with autism spectrum disorder (ASD), but whether asthma and allergy are related to ASD is not well defined. This study examined asthma and allergies in association with ASD and phenotypic subsets. Participants were 560 children with confirmed ASD and 391 typically developing children from the CHildhood Autism Risks from Genetics and the Environment study. Maternally reported child asthma and allergy was compared between cases and controls, and in association with cognitive and behavioral test scores. Prevalence of asthma and overall allergies did not differ between cases and controls, but overall allergy in children with ASD was associated with higher stereotypy scores as measured by the Aberrant Behavior Checklist. In addition, reported food allergies were significantly associated with ASD (adjusted odds ratio = 2.23, 95% confidence interval 1.28, 3.89). Our results suggest food allergies and sensitivities may be more common in children with ASD, and that these issues may correlate with other behaviors.

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

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Web of Science research areas
Behavioral Sciences
Psychology, Developmental
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