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Biological interactions and safety of graphene materials
Journal article   Open access   Peer reviewed

Biological interactions and safety of graphene materials

Ashish C. Jachak, Megan Creighton, Yang Qiu, Agnes B. Kane and Robert H. Hurt
MRS bulletin, v 37(12), pp 1307-1313
01 Dec 2012
DOI: https://doi.org/10.1557/mrs.2012.181
PMID: 25018584
url
https://europepmc.org/articles/pmc4088959View
Accepted (AM)Open Access (License Unspecified),  Open

Abstract

Functionalities
As graphene technologies progress to commercialization and large-scale manufacturing, issues of material and processing safety will need to be more seriously considered. The single word “graphene” actually represents a family of related materials with large variations in number of layers, surface area, lateral dimensions, stiffness, and surface chemistry. Many of these materials have aerodynamic diameters below 5 μm and can potentially be inhaled into the human lung. Graphene materials show several unique modes of interaction with biological molecules, tissues, and cells. The limited literature suggests that graphene materials can be either benign or harmful and that the biological response varies according to a material’s physicochemical properties and biologically effective dose. The present article reviews the current literature on the graphene–biological interface with an emphasis on the mechanisms and fundamental biological responses relevant to material safety and also to potential biomedical applications

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32 citations in Web of Science
34 citations in Scopus

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Web of Science research areas
Materials Science, Multidisciplinary
Physics, Applied
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