Journal article
Causal Inference with Case-Only Studies in Injury Epidemiology Research
Current epidemiology reports, v 9(4), pp 223-232
01 Dec 2022
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Abstract
Purpose of Review We review the application and limitations of two implementations of the "case-only design" in injury epidemiology with example analyses of Fatality Analysis Reporting System data. Recent Findings The term "case-only design" covers a variety of epidemiologic designs; here, two implementations of the design are reviewed: (1) studies to uncover etiological heterogeneity and (2) studies to measure exposure effect modification. These two designs produce results that require different interpretations and rely upon different assumptions. The key assumption of case-only designs for exposure effect modification, the more commonly used of the two designs, does not commonly hold for injuries and so results from studies using this design cannot be interpreted. Case-only designs to identify etiological heterogeneity in injury risk are interpretable but only when the case-series is conceptualized as arising from an underlying cohort. The results of studies using case-only designs are commonly misinterpreted in the injury literature.
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Details
- Title
- Causal Inference with Case-Only Studies in Injury Epidemiology Research
- Creators
- Andrew G. Rundle - Columbia UniversityMichael D. M. Bader - Johns Hopkins UniversityCharles C. Branas - Columbia UniversityGina S. Lovasi - Drexel Univ, Dept Epidemiol & Biostat, Philadelphia, PA 19104 USAStephen J. Mooney - University of WashingtonChristopher N. Morrison - Columbia UniversityKathryn M. Neckerman - Columbia University
- Publication Details
- Current epidemiology reports, v 9(4), pp 223-232
- Publisher
- Springer Nature
- Number of pages
- 10
- Grant note
- K01AA026327 / National Institute on Alcohol Abuse and Alcoholism; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Alcohol Abuse & Alcoholism (NIAAA) R00LM012868 / National Library of Medicine; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Library of Medicine (NLM)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000863122000001
- Other Identifier
- 991020099915804721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health