Journal article
Computational analysis of an axial flow pediatric ventricular assist device
Artificial organs, v 28(10), pp 881-891
Oct 2004
PMID: 15384993
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Longer-term (>2 weeks) mechanical circulatory support will provide an improved quality of life for thousands of pediatric cardiac failure patients per year in the United States. These pediatric patients suffer from severe congenital or acquired heart disease complicated by congestive heart failure. There are currently very few mechanical circulatory support systems available in the United States as viable options for this population. For that reason, we have designed an axial flow pediatric ventricular assist device (PVAD) with an impeller that is fully suspended by magnetic bearings. As a geometrically similar, smaller scaled version of our axial flow pump for the adult population, the PVAD has a design point of 1.5 L/min at 65 mm Hg to meet the full physiologic needs of pediatric patients. Conventional axial pump design equations and a nondimensional scaling technique were used to estimate the PVAD's initial dimensions, which allowed for the creation of computational models for performance analysis. A computational fluid dynamic analysis of the axial flow PVAD, which measures approximately 65 mm in length by 35 mm in diameter, shows that the pump will produce 1.5 L/min at 65 mm Hg for 8000 rpm. Fluid forces (approximately 1 N) were also determined for the suspension and motor design, and scalar stress values remained below 350 Pa with maximum particle residence times of approximately 0.08 milliseconds in the pump. This initial design demonstrated acceptable performance, thereby encouraging prototype manufacturing for experimental validation.
Metrics
Details
- Title
- Computational analysis of an axial flow pediatric ventricular assist device
- Creators
- Amy L Throckmorton - Biomedical Engineering Department, Virginia Artificial Heart Institute, University of Virgina, Charlottesville, VA 22908, USA. alt2c@virginia.eduAlexandrina UntaroiuPaul E AllaireHouston G WoodGaynell Paul MatherneDavid Scott LimBen B PeelerDon B Olsen
- Publication Details
- Artificial organs, v 28(10), pp 881-891
- Publisher
- Wiley; United States
- Grant note
- R01 HL-64378-01 / NHLBI NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000223757100006
- Scopus ID
- 2-s2.0-15444362825
- Other Identifier
- 991014877796304721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Biomedical
- Transplantation