Journal article
Design of a Location-Based Case-Control Study of Built Environment Risk Factors for Pedestrian Fatalities in the U.S
American journal of epidemiology, v 194(7), pp 1976-1983
Jul 2025
PMID: 39393821
Abstract
The location-based case-control design is a useful approach for studies where the exposures of interest are aspects of the environment around the location of a health event such as a pedestrian fatality. In this design locations are the unit of analysis and an enumerated cohort of locations are followed through time for the health events of interest and a case-control study of locations is nested within the cohort. Locations where events occurred (case-locations) are compared to matched locations where these events did not occur (control-locations). We describe the application of this design to the issue of pedestrian fatalities using a cohort of 9,612,698 intersections, 17,737,728 road segments, and 222,318 entrance/exit ramp segments that existed in 2017 across all 384 U.S. Metropolitan Statistical Areas. This cohort of locations was followed up from Jan 1, 2017 to Dec 31, 2018 for pedestrian fatalities using the National Highway Traffic Safety Administration Fatality Analysis Reporting System. In total, 10,587 fatalities were identified as having occurred on cohort locations and 21,174 matched control locations were selected using incidence density sampling. Geographic information systems, spatially linked administrative data sets and virtual neighborhood audits via Google Street View are underway to characterize study locations.
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Details
- Title
- Design of a Location-Based Case-Control Study of Built Environment Risk Factors for Pedestrian Fatalities in the U.S
- Creators
- Andrew G Rundle (Corresponding Author) - Columbia UniversityStephen P Uong - Columbia UniversityMichael D M Bader - Johns Hopkins UniversityEliza W Kinsey - University of PennsylvaniaDirk Kinsey - Columbia UniversityGina S Lovasi - Drexel UniversityStephen J Mooney - University of WashingtonKathryn M Neckerman - Columbia UniversityJames W Quinn - Columbia University
- Publication Details
- American journal of epidemiology, v 194(7), pp 1976-1983
- Publisher
- Oxford University Press
- Grant note
- R00LM012868 / NLM NIH HHS R01AA028552 / National Institutes of Health National Institute on Alcohol Abuse and Alcoholism
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Dana and David Dornsife School of Public Health; Epidemiology and Biostatistics
- Scopus ID
- 2-s2.0-105010705302
- Other Identifier
- 991021910585204721