Journal article
In Vitro Biocompatibility of n‐Type and Undoped Silicon Nanowires
Advanced engineering materials, v 13(1‐2), pp B3-B9
Feb 2011
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The biocompatibility of undoped and n‐type silicon nanowires (SiNWs), synthesized by metal‐catalyzed chemical vapor deposition, was investigated in vitro, and compared with that for SiO2‐coated silicon wafers. In cell interaction studies, L929 mouse fibroblast cells were used, in which MTT assay, AO/PI dye staining, cell proliferation/growth, and changes in cell adhesion/morphology on the surfaces were applied and investigated. Heamocompatibility of these materials were also tested. No significant cytotoxic effects were observed for either the undoped or for the n‐type phosphorus‐doped SiNWs. The cells on the nanowires exhibit high viability, normal nuclear, and morphological structure. They have shown no considerable negative blood response with respect to the control.
Silicon nanowires (SiNWs) have found a wide range of applications in the field of electronics and optics due to their unique chemical and physical properties. The biocompatibility of undoped and n‐type SiNWs, synthesized by metal‐catalyzed chemical vapor deposition, was investigated in vitro, and compared with that for SiO2‐coated silicon wafers. According to the in vitro biocompatibility test results, we conclude that SiNWs may be considered as potential materials for biomedical applications.
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Details
- Title
- In Vitro Biocompatibility of n‐Type and Undoped Silicon Nanowires
- Creators
- Bora Garipcan - Hacettepe UniversitySedat Odabas - Hacettepe UniversityGokhan Demirel - Hacettepe UniversityJonadan Ando Burger - Drexel UniversityStephen S Nonnenmann - Drexel UniversityMichael T Coster - Drexel UniversityEric M Gallo - Drexel UniversityBahram Nabet - Drexel UniversityJonathan E Spanier - Drexel UniversityErhan Piskin - Hacettepe University
- Publication Details
- Advanced engineering materials, v 13(1‐2), pp B3-B9
- Publisher
- Wiley‐VCH Verlag; Weinheim
- Number of pages
- 7
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Electrical and Computer Engineering; Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000287044300001
- Scopus ID
- 2-s2.0-79251616750
- Other Identifier
- 991014878269704721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Materials Science, Multidisciplinary