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Large-Scale Sequencing of Borreliaceae for the Construction of Pan-Genomic-Based Diagnostics
Journal article - Review   Open access   Peer reviewed

Large-Scale Sequencing of Borreliaceae for the Construction of Pan-Genomic-Based Diagnostics

Kayla M Socarras, Benjamin S Haslund-Gourley, Nicholas A Cramer, Mary Ann Comunale, Richard T Marconi and Garth D Ehrlich
Genes, v 13(9)
04 Aug 2022
PMID: 36140772
url
https://doi.org/10.3390/genes13091604View
Published, Version of Record (VoR)Open Access (License Unspecified) Open

Abstract

Borrelia burgdorferi Genome, Bacterial Humans Phylogeny Genomics Lyme Disease
The acceleration of climate change has been associated with an alarming increase in the prevalence and geographic range of tick-borne diseases (TBD), many of which have severe and long-lasting effects-particularly when treatment is delayed principally due to inadequate diagnostics and lack of physician suspicion. Moreover, there is a paucity of treatment options for many TBDs that are complicated by diagnostic limitations for correctly identifying the offending pathogens. This review will focus on the biology, disease pathology, and detection methodologies used for the

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Collaboration types
Domestic collaboration
Web of Science research areas
Genetics & Heredity
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