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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Maternal Exposure to Childhood Abuse is Associated with Mate Selection: Implications for Autism in Offspring
Journal of autism and developmental disorders, v 47(7), pp 1998-2009
01 Jul 2017
PMID: 28393290
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Maternal experience of childhood abuse has been associated with offspring autism. To explore whether familial tendency towards autistic traits-presumably related to genetic predisposition-accounts for this association, we examined whether women who experienced childhood abuse were more likely to select mates with high levels of autistic traits, and whether parental autistic traits accounted for the association of maternal abuse and offspring autism in 209 autism cases and 833 controls. Maternal childhood abuse was strongly associated with high paternal autistic traits (severe abuse, OR = 3.98, 95% CI = 1.26, 8.31). Maternal and paternal autistic traits accounted for 21% of the association between maternal abuse and offspring autism. These results provide evidence that childhood abuse affects mate selection, with implications for offspring health.
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Details
- Title
- Maternal Exposure to Childhood Abuse is Associated with Mate Selection: Implications for Autism in Offspring
- Creators
- Andrea L. Roberts - Harvard UniversityKristen Lyall - Drexel UniversityMarc G. Weisskopf - Harvard University
- Publication Details
- Journal of autism and developmental disorders, v 47(7), pp 1998-2009
- Publisher
- Springer Nature
- Number of pages
- 12
- Grant note
- 1788; 2210 / Autism Speaks grants UM1CA176726 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) A-14917 / United States Army Medical Research and Material Command (USAMRMC) UM1 CA176726 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA W81XWH-08-1-0499 / US Department of Defense (DOD); United States Department of Defense T32MH073124 / NATIONAL INSTITUTE OF MENTAL HEALTH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH) T32MH073124-08; P60AR047782 / US National Institutes of Health (NIH); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA P60AR047782 / NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Arthritis & Musculoskeletal & Skin Diseases (NIAMS)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- A.J. Drexel Autism Institute
- Web of Science ID
- WOS:000403405900008
- Scopus ID
- 2-s2.0-85017172014
- Other Identifier
- 991020100063004721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Psychology, Developmental