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Maternal exposure to intimate partner abuse before birth is associated with autism spectrum disorder in offspring
Journal article   Open access   Peer reviewed

Maternal exposure to intimate partner abuse before birth is associated with autism spectrum disorder in offspring

Andrea L Roberts, Kristen Lyall, Janet W Rich-Edwards, Alberto Ascherio and Marc G Weisskopf
Autism : the international journal of research and practice, v 20(1), pp 26-36
Jan 2016
PMID: 25662292
url
https://europepmc.org/articles/pmc4605895View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Autism Spectrum Disorder - epidemiology Autism Spectrum Disorder - psychology Fear - psychology Female Humans Intimate Partner Violence - psychology Intimate Partner Violence - statistics & numerical data Mothers - statistics & numerical data Odds Ratio Pregnancy Pregnancy Complications - epidemiology Pregnancy Complications - psychology Risk Factors Surveys and Questionnaires
We sought to determine whether maternal (a) physical harm from intimate partner abuse during pregnancy or (b) sexual, emotional, or physical abuse before birth increased risk of autism spectrum disorder. We calculated risk ratios for autism spectrum disorder associated with abuse in a population-based cohort of women and their children (54,512 controls, 451 cases). Physical harm from abuse during pregnancy was not associated with autism spectrum disorder. However, autism spectrum disorder risk was increased in children of women who reported fear of partner or sexual, emotional, or physical abuse in the 2 years before the birth year (abuse in the year before the birth year: risk ratio = 1.58, 95% confidence interval = 1.04, 2.40; abuse in both of the 2 years before the birth year: risk ratio = 2.16, 95% confidence interval = 1.33, 3.50). Within-family results were similar, although did not reach statistical significance. Association of intimate partner abuse before the child's birth year with autism spectrum disorder in the child was not accounted for by gestation length, birth weight, maternal smoking or alcohol consumption during pregnancy, gestational diabetes, preeclampsia, or history of induced abortion.

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Web of Science research areas
Psychology, Developmental
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