Journal article
Mechanical Circulatory Support of the Right Ventricle for Adult and Pediatric Patients With Heart Failure
ASAIO journal (1992), v 65(2), pp 106-116
Feb 2019
PMID: 29757759
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The clinical implementation of mechanical circulatory assistance for a significantly dysfunctional or failing left ventricle as a bridge-to-transplant or bridge-to-recovery is on the rise. Thousands of patients with left-sided heart failure are readily benefitting from these life-saving technologies, and left ventricular failure often leads to severe right ventricular dysfunction or failure. Right ventricular failure (RVF) has a high rate of mortality caused by the risk of multisystem organ failure and prolonged hospitalization for patients after treatment. The use of a blood pump to support the left ventricle also typically results in an increase in right ventricular preload and may impair right ventricular contractility during left ventricular unloading. Patients with RVF might also suffer from severe pulmonary dysfunction, cardiac defects, congenital heart disease states, or a heterogeneity of cardiophysiologic challenges because of symptomatic congestive heart failure. Thus, the uniqueness and complexity of RVF is emerging as a new domain of significant clinical interest that motivates the development of right ventricular assist devices. In this review, we present the current state-of-the-art for clinically used blood pumps to support adults and pediatric patients with right ventricular dysfunction or failure concomitant with left ventricular failure. New innovative devices specifically for RVF are also highlighted. There continues to be a compelling need for novel treatment options to support patients with significant right heart dysfunction or failure.
Metrics
Details
- Title
- Mechanical Circulatory Support of the Right Ventricle for Adult and Pediatric Patients With Heart Failure
- Creators
- Steven G Chopski - Drexel UniversityNohra M Murad - Drexel UniversityCarson S Fox - Drexel UniversityRandy M Stevens - St. Christopher's Hospital for ChildrenAmy L Throckmorton - Drexel University
- Publication Details
- ASAIO journal (1992), v 65(2), pp 106-116
- Publisher
- Lippincott
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics; School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000457719900008
- Scopus ID
- 2-s2.0-85060616858
- Other Identifier
- 991019167622404721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Biomedical
- Transplantation