Journal article
Numerical design and experimental hydraulic testing of an axial flow ventricular assist device for infants and children
ASAIO journal (1992), v 53(6), pp 754-761
Nov 2007
PMID: 18043161
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Mechanical circulatory support options for infants and children are very limited in the United States. Existing circulatory support systems have proven successful for short-term pediatric assist, but are not completely successful as a bridge-to-transplant or bridge-to-recovery. To address this substantial need for alternative pediatric mechanical assist, we are developing a novel, magnetically levitated, axial flow pediatric ventricular assist device (PVAD) intended for longer-term ventricular support. Three major numerical design and optimization phases have been completed. A prototype was built based on the latest numerical design (PVAD3) and hydraulically tested in a flow loop. The plastic PVAD prototype delivered 0.5-4 lpm, generating pressure rises of 50-115 mm Hg for operating speeds of 6,000-9,000 rpm. The experimental testing data and the numerical predictions correlated well. The error between these sets of data was found to be generally 7.8% with a maximum deviation of 24% at higher flow rates. The axial fluid forces for the numerical simulations ranged from 0.5 to 1 N and deviated from the experimental results by generally 8.5% with a maximum deviation of 12% at higher flow rates. These hydraulic results demonstrate the excellent performance of the PVAD3 and illustrate the achievement of the design objectives.
Metrics
Details
- Title
- Numerical design and experimental hydraulic testing of an axial flow ventricular assist device for infants and children
- Creators
- Amy L Throckmorton - Mechanical Engineering Department, School of Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, USAAlexandrina UntaroiuPaul E AllaireHouston G WoodD Scott LimMichael A McCullochDon B Olsen
- Publication Details
- ASAIO journal (1992), v 53(6), pp 754-761
- Publisher
- Lippincott; United States
- Grant note
- R01 HL64378-01 / NHLBI NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000251229600024
- Scopus ID
- 2-s2.0-36549056164
- Other Identifier
- 991014878121504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Engineering, Biomedical
- Transplantation