Journal article
Prevalence and Predictors of Long-term Opioid Use After Pelvic Fractures
The American surgeon, Vol.89(9), pp.3710-3715
01 Sep 2023
PMID: 37144563
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background
Opioids are effective in short-term pain treatment; however, their long-term effectiveness is unconfirmed. Many patients are exposed to opioids after pelvic injuries with little known about persistent use afterward. We assessed the prevalence and predictors of long-term opioid use following pelvic fractures.
Materials and Methods
This retrospective study enrolled 277 patients with acute pelvic fractures over five years. Daily and total morphine milligram equivalents (MME) were calculated. The primary outcome was long-term opioid use (LOU) defined as ongoing opioid use 60-90 days post-discharge. The secondary outcome was intermediate-term opioid use (IOU) defined as ongoing opioid use 30-60 days post-discharge. Univariable and logistic regression analyses were performed.
Results
Median (interquartile range) total inpatient opioid MME was 422 (157-1667) with a median daily MME of 69 (26-145). Long-term opioid use occurred in 16%, and IOU occurred in 29%. Univariable analysis found that total and daily inpatient opioid use were each significantly associated with LOU (median MME, 1241 vs 371; median MMEs, 127.7 vs 59.2, respectively) and IOU (median MME, 1140 vs 326; median MMEs, 111.8 vs 57.9, respectively). Logistic regression analysis found daily inpatient MME >= 50 (odds ratio [OR] 3.027, 95% confidence interval [CI] 1.059-8.652]) and pelvic fracture type (Tile B/C) (OR 2.992 [CI 1.324-6.763])were independent predictors of LOU.
Conclusion
Total and daily inpatient opioid use were significantly associated with LOU and IOU. Patients who received >= 50 MME/inpatient day had a higher likelihood of LOU. This study seeks to inform clinical decisions for pain management to prevent adverse outcomes.
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Details
- Title
- Prevalence and Predictors of Long-term Opioid Use After Pelvic Fractures
- Creators
- Nicole Ann Elvambuena Villa - Drexel University, College of MedicineKristina Shum - Drexel University, College of MedicineAllison Atkinson - Drexel University, College of MedicineAdrian Ong - Reading HospitalAllison Muller - Reading HospitalEduardo Espiridion - Drexel University, College of Medicine
- Publication Details
- The American surgeon, Vol.89(9), pp.3710-3715
- Publisher
- Sage
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychiatry; College of Medicine; Surgery
- Web of Science ID
- WOS:000981757200001
- Scopus ID
- 2-s2.0-85158890233
- Other Identifier
- 991021861211604721
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- Web of Science research areas
- Surgery