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Testing of aggregation measurement techniques for intramembranous particles
Journal article   Open access   Peer reviewed

Testing of aggregation measurement techniques for intramembranous particles

J T Donnell and L X Finegold
Biophysical journal, v 35(3), pp 783-798
01 Sep 1981
PMID: 7272460
url
https://doi.org/10.1016/s0006-3495(81)84827-8View
Published, Version of Record (VoR)Open Access (Publisher-Specific) Open
url
https://doi.org/10.1016/S0006-3495(81)84827-8View
Published, Version of Record (VoR) Open

Abstract

Under various physiological and nonphysiological conditions, the intramembranous particles, as seen by freeze-fracture electron microscopy, may be in various degrees of aggregation. To compare various schemes for the measurement of the degree of aggregation, a computer program has been used to generate simulated aggregations. A simple and adequate technique for quantifying the degree of aggregation, which is practical for the electron microscopist, is presented.

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Biophysics
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