Journal article
The Use of Tranexamic Acid in Joint Replacement Surgery
Orthopaedic nursing, v 34(2), pp 89-92
01 Mar 2015
PMID: 25785617
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Perioperative bleeding is a prevalent risk of elective joint replacement surgery that can lead to allogeneic blood transfusions, delayed discharge, and slowed physical therapy progress. Antifibrinolytics such as tranexamic acid (TXA) have been used in various surgical procedures to reduce bleeding; however, the use of TXA in orthopaedic surgery is not widespread. The purpose of this article is to determine whether the use of TXA in joint replacement surgery reduces total blood loss and lowers the need for allogeneic blood transfusions without adding additional surgical risk and cost. All reviewed meta analyses and systematic reviews analyzed did show a statistically significant reduction in total blood loss and reduction in the need for allogeneic blood transfusions. Therefore, researchers conclude that intravenous TXA use does decrease total blood loss and allogeneic blood transfusion needs. Thus, its use should be included in orthopaedic clinical practice guidelines due to its overall positive effect on outcomes.
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Details
- Title
- The Use of Tranexamic Acid in Joint Replacement Surgery
- Creators
- Sarah Suggs - Joint Replacement InstituteKaryn Holt - Drexel University
- Publication Details
- Orthopaedic nursing, v 34(2), pp 89-92
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 4
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:000351672400003
- Scopus ID
- 2-s2.0-84950237490
- Other Identifier
- 991021867052704721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Nursing
- Orthopedics