Journal article
The formation of multilamellar vesicles from saturated phosphatidylcholines and phosphatidylethanolamines: morphology and quasi-elastic light scattering measurements
Chemistry and physics of lipids, v 54(2), pp 131-146
1990
PMID: 2364473
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The aggregation properties of diacyl phosphatidylcholines (PC) and phosphatidylethanolamines (PE), with linear symmetrical saturated chains, were characterized at temperatures below and above the lipid solid to fluid transition. PEs in the solid state form bundles of closely apposed flat bilayer stacks which at the solid to fluid transition temperature fold into closed multilamellar vesicles. On the other hand, PCs in the solid state form extended multilayer sheets. At the solid to fluid transition, multilamellar vesicles appear to “bud off” from the surface. Quasi-elastic light scattering (QELS) measurements indicated that for the PEs, bundle size is independent of acyl chain length
n, but that the sizes of vesicles which form at the solid to fluid transition are positively correlated with
n. The results of temperature jump experiments showed that once the transition temperature was reached, vesicle formation was largely complete within 30 s.
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Details
- Title
- The formation of multilamellar vesicles from saturated phosphatidylcholines and phosphatidylethanolamines: morphology and quasi-elastic light scattering measurements
- Creators
- Michael A. Singer - Queen's UniversityLeonard Finegold - Drexel UniversityPaul Rochon - Royal Military College of CanadaThomas J. Racey - Royal Military College of Canada
- Publication Details
- Chemistry and physics of lipids, v 54(2), pp 131-146
- Publisher
- Elsevier Ireland Ltd
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1990DF52300005
- Scopus ID
- 2-s2.0-0025313473
- Other Identifier
- 991019173628304721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Biochemistry & Molecular Biology
- Biophysics