Journal article
Treatment of neonatal necrotizing tracheobronchitis with extracorporeal membrane oxygenation and bronchoscopy
Journal of pediatric surgery, v 23(9), pp 798-801
01 Sep 1988
PMID: 3183890
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Necrotizing tracheobronchitis has recently been described as a complication of mechanical ventilation of newborns with respiratory failure. Despite the use of bronchoscopy, 45% of the reported patients to date have died. In this study, we report the use of extracorporeal membrane oxygenation (ECMO) to stabilize two patients with necrotizing tracheobronchitis. While supported by bypass, both patients underwent prolonged bronchoscopies with removal of extensive amounts of tracheal debris. ECMO provided efficient oxygenation in the face of near total airway occlusion, and permitted far more extensive bronchoscopic debridement and lavage than would have been possible if the lungs were required for oxygenation. In addition, ECMO provided a period of lung “rest” during which ventilator settings were reduced, thus minimizing further barotrauma and allowing for lung and airway healing. Both patients recovered without significant respiratory sequelae. ECMO and bronchoscopy are effective forms of therapy for patients with life-threatening necrotizing tracheobronchitis when conventional modalities of treatment have failed.
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Details
- Title
- Treatment of neonatal necrotizing tracheobronchitis with extracorporeal membrane oxygenation and bronchoscopy
- Creators
- Eric J. Michael - Philadelphia UniversityDavid Zwillenberg - Philadelphia UniversityAnthony Furnari - Philadelphia UniversityLisamarie Sheppard - Philadelphia UniversityHemant J. Desai - Philadelphia UniversityPhilip J. Wolfson - Philadelphia UniversityNancy B. RobinsonMichael Kornhauser - Philadelphia UniversitySylvester Mobley - Philadelphia UniversityPaul A. Branca - Philadelphia University
- Publication Details
- Journal of pediatric surgery, v 23(9), pp 798-801
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:A1988Q187200003
- Scopus ID
- 2-s2.0-0023712183
- Other Identifier
- 991021862408404721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Pediatrics
- Surgery