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Trends of Opioid Use Disorder and Associated Factors in Hospitalized Patients With Arthritis
Journal article   Open access   Peer reviewed

Trends of Opioid Use Disorder and Associated Factors in Hospitalized Patients With Arthritis

Adeolu O. Oladunjoye, Olubunmi O. Oladunjoye, Jean Gauvin, Maria Ruiza Yee and Eduardo D. Espiridion
Curēus (Palo Alto, CA), v 12(9), pp e10203-e10203
02 Sep 2020
DOI: https://doi.org/10.7759/cureus.10203
PMID: 33033680
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.7759/cureus.10203View
Published, Version of Record (VoR)CC BY V4.0,  Open

Abstract

General & Internal Medicine Life Sciences & Biomedicine Medicine, General & Internal Science & Technology
Introduction Opioid use was primarily limited to acute pain, postsurgical care, and end of life care setting but now is the most prescribed medication for chronic pain. Arthritis is a chronic disease associated with chronic pain. Given limited options for pain relief in the patient population, these patients are often prescribed opioids and are at increased risk of opioid use disorder (OUD). Therefore, our study aimed to identify factors associated with OUD in patients with arthritis. Methods We analyzed hospitalized adult patients with arthritis with and without OUD using discharge data from National Inpatient Sample (NIS) over five years from January 1, 2010, to December 31, 2014. We looked at trends of OUD in hospitalized patients with arthritis and compared demographic and clinical characteristics of patients with and without OUD using Student's t-test and chi-square test. Multivariate analysis was also used to adjust for variables. Results A total of 21,396,252 arthritis hospitalizations were identified during the five-year study period among which 227,608 had OUD. The prevalence of OUD in arthritis hospitalization increased over the five-year period by 43%. After adjusting for other variables, mental health (OR 2.50 (2.43-2.58)), and substance use (OR 6.39 (6.14-6.66)) disorders were associated with increased odds of OUD. Conclusion The prevalence of OUD among patients with arthritis increased over the five-year study period. Mental health and substance use disorders were associated with increased odds of OUD. More studies are needed to explore alternative pain management options for arthritis patients particularly in those with mental health and substance use disorders.

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Collaboration types
Domestic collaboration
Web of Science research areas
Rheumatology
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